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Dimethylformamide
N. N-dimethylformamide (DMF) is widely used as a pharmaceutical solvent. N. N-dimethylformamide is a dipolar protophilic solvent with physical and chemical properties, making it suitable as a solvent for capillary electrophoresis (CE)
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Product Description
Dimethylformamide (DMF) is a transparent liquid that is miscible with water and most organic solvents. It is a commonly used solvent for
chemical reactions. Pure dimethylformamide is odorless,However, industrial grade or deteriorated dimethylformamide has a fishy odor
because it contains impurities of dimethylamine. The name comes from the fact that it is a dimethyl substitute of formamide (formamide),
with both methyl groups located on N (nitrogen) atoms.Dimethylformamide is a highly boiling polar (hydrophilic) non proton solvent that
can promote the progression of SN2 reaction mechanisms. Dimethylformamide is manufactured using formic acid and dimethylamine.
Dimethylformamide in strong bases such as sodium hydroxide or Strong acids such as hydrochloric acid or sulfuric acid are unstable in
the presence (especially at high temperatures) and hydrolyze into formic acid and dimethylamine.
Item | N,N-Dimethylformamide |
Appearance | Colorless Transparent Liquid |
Molecular Weight | 73.09380 |
Density | 0.948 g/mL at 20 °C |
Boiling Point | 153 °C(lit.) |
Melting Point | -61 °C |
Flash Point | 136 °F |
Refractivity | n20/D 1.430(lit.) |
Application
Dimethylformamide is most widely used in amide solvents. Mainly used as a solvent for spinning polyacrylonitrile fibers. As a gas absorbent in
the petrochemical industry, it is used for selective absorption of acetylene and separation and refining of butadiene.
Used as a solvent in the production of synthetic leather. Used as a stationary phase in gas-liquid chromatography analysis. Used to synthesize
chlorpyrifos in pesticides. Used in medicine to synthesize sulfadiazine, doxycycline, cortisone, vitamin B6, etc.
In addition, dimethylformamide is a non-protonic polar solvent and an excellent solvent for many organic synthesis reactions.
Package
Customized packaging can also be carried out using iron bucket packaging
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